Every single GameCube game can at least boot in Dolphin 5.0. Except one. Star Wars: The Clone Wars and its complex way of using the PowerPC Memory Management Unit rendered it unplayable in Dolphin up to this day. But finally as of Dolphin 5.0-540, this challenge has come and gone: Dolphin can finally boot every single GameCube game in the official library.
So what makes Star Wars: The Clone Wars so special? To truly understand what's going on, you need to have some knowledge on how the PowerPC's processor handles memory management and how Dolphin emulates it.